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The pain models were prepared by injection of acetic acid and uterospasm model in the female mouse was induced by diethylstilbestrol and pitocin. 乙烯雌酚、催产素诱发的雌性小鼠子宫痉挛性疼痛和醋酸性疼痛的扭体反应和大鼠高脂血症模型。